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رزومه
Curriculum Vitae
1) مشخصات فردي
نام : بیژن
نام خانوادگي: ملائکه نیکوئی
جنسيت: مرد
رشته تحصيلي: فارماسیوتیکس
گروه آموزشي: فارماسیوتیکس
مرتبه علمي: دانشیار
آدرس محل كار: مشهد – بلوار وکیل آباد – مجتمع دانشگاهی – دانشکده داروسازی – صندوق پستی 1365-91775
تلفن محل كار: 8823255 (98511+)
2) تحصيلات دانشگاهي
1) دکترای عمومی داروسازی، دانشگاه علوم پزشكي تبریز، (مهر ماه 1373 لغايت شهريور ماه 1378)
2) دکترای تخصصی (PhD) فارماسیوتیکس، دانشگاه علوم پزشکی مشهد (مهرماه 1379 لغایت شهریورماه 1385)
3) تجربيات حرفه اي
4) تجربيات آموزشي
1) استاديار فارماسیوتیکس، دانشكده داروسازی، دانشگاه علوم پزشكي مشهد، (مهرماه 1385 تا مردادماه 1390)
2) دانشیار فارماسیوتیکس، دانشكده داروسازی، دانشگاه علوم پزشكي مشهد، (مردادماه 1390 تاکنون)
5) عناوين و امتيازات ويژه
1) رتبه سوم در گروه علوم دارویی، جشنواره هفته پژوهش دانشگاه علوم پزشكي مشهد سال 1389
6) فعاليت هاي پژوهشي
الف) انتشار مقاله در ژورنالهاي علمي پژوهشي سطح ISI) : I)
1) Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2004, Preparation and characterization of biodegradable microspheres encapsulated with cyclosporine A using different grades of PLGA, Iranian Journal of Basic Medical Sciences, 7, 4, 240-249.
2) Jaafari M. R., Malaekeh-Nikouei B., Nasirli H., Hosseinzadeh H., 2005, Formulation of topical liposomes encapsulated with triamcinolone and comparison of their anti-inflammatory effects with available conventional topical ointment in mice, Iranian Journal of Basic Medical Sciences, 8, 3, 195-201.
3) Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2006, The effect of different grades of PLGA on characteristics of microspheres encapsulated with cyclosporine A, Current Drug Delivery, 3, 4, 343-349 .
4) Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Davies N. M., 2006, The effect of complexation on characteristics and drug release of PLGA microspheres loaded by cyclosporine-cyclodextrin complex, Journal of Drug Delivery Science and Technology, 16(5), 345-350.
5) Malaekeh-Nikouei B., Nassirli H., Davies N. M., 2007, Enhancement of cyclosporine aqueous solubility using α- and hydroxypropyl β-cyclodextrin mixtures, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 59 (3-4), 245-250.
6) Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., 2008, Preparation, characterization and mucoadhesive properties of chitosan coated microspheres encapsulated with cyclosporine A, Drug Development and Industrial Pharmacy, 34, 5, 492-498.
7) Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiee A., 2008, The Enhancement of Immunosuppressive Effects of Cyclosporine A on Human T-Cells Using Fusogenic Liposomes, Colloids and Surfaces B:Biointerfaces, 67, 238-244.
8) Abrishami M., Zarei-Ghanavati S., Soroush D., Rouhbakhsh M., Jaafari M. R., Malaekeh-Nikouei B., 2009, Preparation, characterization and in vivo evaluation of nanoliposomes encapsulated bevacizuamb for Intravitreal administration, Retina, 29, 5, 699-703 (IF=2.77).
9) Ramezani M., Khoshhamdam M., Dehshahri A.,Malaekeh-Nikouei B., 2009, The influence of size, lipid composition and bilayer Tm on the transfection efficiency of nanolipoplexes, Colloids and Surfaces B:Biointerfaces, 72(1), 1-5 (IF=2.78).
10) Malaekeh-Nikouei B., Malaekeh-Nikouei M., Kazemi Oskuee R., Ramezani M., 2009, Preparation, characterization and transfection efficiency of nanoliposomes modified with oligoamines as gene carrier, Nanomedicine: Nanotechnology, Biology, and Medicine, 5, 457–462 (IF=4.88).
11) Malaekeh-Nikouei B., Sajadi Tabassi S.A., Ashari H., Gholamzadeh A., 2009, Evaluation the effect of cyclodextrin complexation on aqueous solubility of fluorometholoneto achieve ophthalmic solution, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 65, 335-340 (IF=1.22).
12) Ramezani M., Khakshoor T., Malaekeh-Nikouei M., Malaekeh-Nikouei B., 2010,The effect of linear PEI on characteristics and transfection efficiency of PEI-based cationic nanoliposomes, Iranian Journal of Basic Medical Sciences, Vol. 14, No. 1, 82-88.
13) Malaekeh-Nikouei B., Banaee T., Aghamohammadian J., Mosallaei N., Mohajeri SA., 2011, Quantitative LC Analysis of Cyclosporine A in Ocular Samples, Chromatographia, 73:817–821, (IF=1.07).
14) Motaharinia J., Ramezani M., Malaekeh-Nikouei M., Malaekeh-Nikouei B., Liposome-linear polyethyleneimine-DNA Nanocomplexes for Gene Delivery: Preparation, Characterization and In Vitro Transfection Activity, Current Nanoscience, 7, 587-593 (IF=1.87).
15) Mousavi S.H., Moallem S.A., Mehri S., Shahsavand S., Nassirli, Malaekeh-Nikouei B., Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form, Pharmaceutical Biology 2011; 49(10): 1039–1045 (IF=0.63).
16) Malaekeh-Nikouei B., Sajadi Tabassi S.A., Gerayeli G., Arab Salmani M., Gholamzadeh A., 2011, The effect cyclodextrin mixtures on the aqueous solubility of beclomethasone dipropionate, Journal of Inclusion Phenomena and Macrocyclic Chemistry (Accepted) (IF=1.16).
17) Mohajeri SA, Malaekeh-Nikouei B., Development of a pH-responsive drug delivery system for diclofenac using molecularly imprinted polymers, Drug Development and Industrial Pharmacy (Accepted) (IF=1.39).
18) Malaekeh-Nikouei B., Abbasi Ghaeni F., Motamedshariaty V., Mohajeri SA, 2011, Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses, Journal of Applied Polymer Science (English) (Accepted) (IF=1.24).
ب) انتشار مقاله در ژورنالهاي علمي پژوهشي سطح Index Medicus, Pubmed, Medline) : II )
1. Malaekeh-Nikouei B., Davies N. M., 2009, Double loading of cyclosporine A in liposomes using cyclodextrin complexes, PDA Journal of Pharmaceutical Science and Technology, March-April, 63(2), 139-148.
ج) انتشار مقاله در ژورنالهاي علمي پژوهشي سطح Scopus, Chemical Abstract, Embase, Biological Abstract) : III )
1. Hasanzadeh D., Malaekeh-Nikouei B., 1997, Quantitative analysis of H2-blockers by FT-IR: comparison with HPLC method, Pharmaceutical Sciences (Journal of Tabriz Faculty of Pharmacy), 3, 25-32.
2. Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiee A., 2005, Preparation of fusogenic liposomes encapsulated with cyclosporine A and evaluation of its immunosuppressive effects on human T-cells, Pharmaceutical Sciences (Journal of Tabriz Faculty of Pharmacy), 2, 1-9.
3. Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., 2007, Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A, Saudi Pharmaceutical Journal, 15, 3-4, 176-182.
4. Malaekeh-Nikouei B., Abrishami M., Zarei S., 2008, Liposomal formulation of bevasizuamb for intravitreal administration: increased half-life, decreased side effects, Iranian Journal of Medical Hypotheses and Ideas, 2:4.
5. Malaekeh-Nikouei B., Golmohammadzadeh S., Hosseini M., Nassirli H., 2011, Preparation and characterization of liposomes encapsulated with clindamycin and tretinoin, Pharmacie Globale (IJCP), 6 (03),
6. Ramezani M., Malaekeh-Nikouei B., Motaharinia J., Malaekeh-Nikouei M., 2011, Glactosylated liposome-polyethyleneimine-DNA nanocomplexes as a non-viral vector, Pharmacie Globale (IJCP), 10 (03) (English).
د) انتشار مقاله در ژورنالهاي علمي پژوهشي سطح IV: (ساير سايتهاي تخصصي)
1.Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Davies N. M., 2005, Preparation and characterization of PLGA microspheres loaded by cyclosporine-cyclodextrin complex, Iranian Journal of Pharmaceutical Sciences, 1, 4, 195-201.
2. Asili J., Mosallaei N., Shaterzadeh A., Malaekeh-Nikouei B., 2011, Preparation and characterization of liposomes containing methanolic extract of aerial parts of Platycladus orientalis (L.) Franco, Avicenna Journal of Phytomedicine, (English) (Accepted).
هـ) انتشار مقاله در ژورنالهاي علمي پژوهشي اندكس نشده:
و) ارائه مقاله دركنگره ها يا سمينارهاي خارجي:
1) Malaekeh-Nikouei B., Ramezani M., Arabi L., Transfection efficiency of hydrophobic polyethyleneimine-based cationic nanoliposomes, Nanoscience and Nanotechnology 2011, September 19-23, 2011, Italy.
2) Malaekeh-Nikouei B., Ramezani M., and Malaekeh-Nikouei M.,Galactosylated liposmes-polyethyleneimine-DNA Nanocomplexes for gene delivery, Nano Thailand 2010, November 18-20, 2010, Thailand.
3) Malaekeh-Nikouei B., Ramezani M., and Malaekeh-Nikouei M., Preparation, Characterization and Transfection Efficiency of Galactosylated Nanolipoplexes as a Gene Carrier, 2010 Singapore Symposium on Drug Delivery Systems, January 20-24, 2010, Singapore.
4) Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Afshin Samiei, The effect of phospholipid type and size on immunosuppressive activities of liposomes encapsulated with cyclosporine A, 11th Liposome Research Days Conference, July 2008, Yokohama, Japan.
5) Sajadi S. A., Malaekeh-Nikouei B., Jaafari M. R., Davies N. M., The effect of complexation on characteristics of and drug release from PLGA microspheres loaded by cyclosporine-cyclodextrin complex, 33rd Annual Meeting and Exposition of the Controlled Release Society, July 2006, Vienna, Austria.
6) Sajadi S. A., Malaekeh-Nikouei B., Jaafari M. R., Preparation and characterization of biodegradable microspheres encapsulated with Cyclosporine A using different grades of PLGA, 1ST Pharmaceutical Sciences Fair & Exhibition, June 2005, Nice, France.
ز) ارائه مقاله دركنگره ها يا سمينارهاي داخلي:
1) Malaekeh-Nikouei B., Zarei-Ghanavati S., Pourmazar R., Seyedi S.,Microspheres containing triamcinolone acetonide for intravitreal administration: preparation, characterization and in vivo evaluation, 5th Iranian Controlled Release Conference, October 4-6, 2011, Mashhad, Iran.
1) Malaekeh-Nikouei B., Ramezani M., Motaharinia J., and Malaekeh-Nikouei M., The Cationic Liposome-Polyethyleneimine-DNA Complexes for Gene Delivery: Preparation, Characterization, and Transfection In Vitro, 12th Iranian Pharmaceutical Sciences Conference, August 2-5, 2010, Zanjan, Iran.
2) Malaekeh-Nikouei B., Abrishami M., Zarei-ghanavati S., Soroush D., Majid Rouhbakhsh M., Jaafari M. R., Preparation, characterization and in vivo evaluation of nanoliposomes encapsulated bevacizuamb (Avastin) for intravitreal administration, The Specialized Congress of Nanomedicine, Nanobiotechnology, Nanobiosensors and Nanomaterials,July 14-16, 2009 , Mashhad, Iran.
3) Malaekeh-Nikouei B., Ramezani M., Nazari S., Khakshour T., Preparation, characterization and transfection efficiency of nanoliposmes modified with lipopolymers constructed from polyethyleneimine and acrylate derivatives, 4th Iranian Controlled Release Conference, October 6-8, 2009, Zanjan, Iran
4) Malaekeh-Nikouei B., Ramezani M., Malaekeh-Nikouei M., Kazemi Oskuee R., Preparation, characterization and transfection efficiency of nanoliposomes modified with oligoamines as gene carrier, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.
5) Gholamzadeh A., Ashari H., Malaekeh-Nikouei B., Sajadi Tabassi S.A., Evaluation of sulphobutylether β-cyclodextrin and hydroxypropyl γ-cyclodextrin complexation on aqueous solubility of fluorometholone, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.
6) Shahsavand S., Mehri S., Moallem S.A., Mosavi S.H.,Malaekeh-Nikouei B., Assessment of cytotoxic and apoptogenic properties of crocin and its nanoliposomes in various cancer cell lines, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.
7) Mehri S., Shahsavand S., Moallem S.A., Mosavi S.H.,Malaekeh-Nikouei B., Assessment of cytotoxic and apoptogenic properties of safranal and its nanoliposomes in various cancer cell lines, 11th Iranian Pharmaceutical Sciences Conference, Aug 2008, Kerman, Iran.
8) Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A, The Third Iranian Conference of Novel Drug Delivery Systems, June 2007, Tehran, Iran.
9) Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R., Preparation and characterization of chitosan coated microspheres encapsulated with cyclosporine A, 10th Iranian Pharmaceutical Sciences Conference, Aug 2006, Tehran, Iran.
10) Malaekeh-Nikouei B., Jaafari M. R., Sajadi S. A., Samiei A., The enhancement of immunosuppressive effects of cyclosporine A on human T-cells using fusogenic liposomes, 10th Iranian Pharmaceutical Sciences Conference, Aug 2006, Tehran, Iran.
7) كتب تأليف/ ترجمه شده
الف) کتب تالیفی:
1) سامانه های دارورسانی با اندازه نانو، چاپ اول، انتشارات دانشگاه علوم پزشكي مشهد، مشهد، سال 1390.
ب) كتب ترجمه شده:
1) استوارت باربارا، ” طیف بینی مدرن مادون قرمز “، ترجمهي حسن زاده. داود، ملائکه. بیژن، چاپ اول، انتشارات دانشگاه علوم پزشكي مشهد، مشهد، سال 1380.
8) مسئولیت های اجرائی
1) عضو كميته كارشناسي علوم پايه معاونت پژوهشی دانشگاه علوم پزشکی مشهد از سال 1387 تا سال 1389
2) مدیر اجرایی مجله علوم پایه پزشکی ایران، از سال 1382 تاکنون
3) عضو تمام وقت مرکز تحقیقات نانوفناوری از سال 1388 تاکنون
4) مسئول آزمایشگاه داروسازی صنعتی دانشکده داروسازی از سال 1388 تاکنون
5) دبیر اجرایی همایش تخصصی جایگاه نانوداروها، نانوزیست فناوری و..... در سال 1389
6) مدیر عامل داروخانه آموزشی 22 بهمن از سال 1389 تاکنون
7) دبیر اجرایی پنجمین همایش سامانه های نوین دارورسانی ایران در سال 1390
9) عضویت در سازمان ها
1) عضو انجمن متخصصین علوم دارویی ایران
2) عضو انجمن نانوفناوری ایران
10) علایق پژوهشی
1) سيستم هاي نوين داروسازي نظير : ميكروسفرها، نانوسفرها، ليپوزوم ها، ليپوسفرها
2) طراحي وكتورهاي غير ويروسي و انتقال ژن
3) بررسي افزايش محلوليت داروهااز طريق كمپلكس شدن با سيكلودكسترين ها
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دانشکده داروسازی
