Curriculum Vitae
Mehrdad Iranshahi
PERSONAL HISTORY:
First Name: Mehrdad
Last Name: Iranshahi
Nationality: Iranian
Date of birth: 22th sep.1974
Place of birth: Mashad,Iran
Marital Status: Married
Language: Persian, English
Mailing Address: Department of Pharmacognosy, school of Pharmacy, Vakilabad Avenue , Mashhad , Iran.
P.O.Box.: 91775-1365
Tel.: +98-511-8823255-66
Fax.: +98-511-8823251
E-mail: iranshahim@mums.ac.ir or Iranshahi@yahoo.com
RESEARCH INTERESTS :
1- Isolation, synthesis and structure elucidation of natural products.
2- Biological activity of natural products, especially prenylated natural products.
papers:
1-Iranshahi M, Amin GR, Amini M, Shafiee A (2003). Sulfur containing derivatives from Ferula persica var. latisecta. Phytochemistry, 63, 965-966.
2- Iranshshi M, Amin GR, Jalalizadeh H, Shafiee A (2003). new germacrane derivative from Ferula persica Willd. Var Latisecta Chamberlain. Pharmaceutical biology, 41, 6, 431-433.
3- Ziaee V, Jalalizadeh H, Iranshahi M, Shafiee A (2004). Improved synthesis of vasicinone. Iranian Journal of Chemistry and Chemical Engineering, 23, 33-36.
4- Iranshahi M, GR Amin, Abbas Shafiee (2004). A new coumarin from Ferula persica . Pharmaceutical biology, 42, 6, 440-442.
5- Iranshahi M, Shahverdi AR, Mirjani R, Amin GR, Abbas Shafiee (2004). Umbellipreninfrom Ferula persica roots inhibits the red pigment production in Serratia marcescens . Zeitschrift für Naturforschung, 59 c, 506-508.
6- Monsef HR, Ghobadi A,Iranshahi M, Abdollahi M (2004). Antinociceptive effects of Peganum harmala L. alkaloid extract on mouse formalin test. Journal of pharmacy and pharmaceutical sciences, 7, 65-69.
7- Shahverdi AR, Mirjani R, Amin GR, Shafiee A,Iranshahi M (2005). Bleaching of Serratia marcescens by some coumarins: A spectrophotometric study. Journal of Basic Microbiology, 45, 470-474.
8- Mirjani R, Shahverdi AR, Iranshahi M, Amin GR, Shafiee A (2005). Identification of Antifungal Compounds from Ferula persica var. persica. Pharmaceutical Biology, 43, 293-295.
9- Shahverdi AR, Iranshahi M, Mirjani R, Jamalifar H, Amin GR, Shafiee A(2005). Bioassay-guided isolation and identification of an antibacterial compound from Ferula persica var.persica roots. DARU, 13, 17-19.
10- Fakhimi A, Iranshahi M, Emami SA, Amin-Ar-Ramimeh E, Zarrini G, Shahverdi AR (2006). Sophoraflavanone G from Sophora pachycarpa enhanced the antibacterial activity of gentamycin against Staphylococcus aureus. Zeitschrift für Naturforschung, 61c, 769-772.
11- Iranshahi M, Amin GR, Salehi Sourmaghi MH, Shafiee A, Hadjiakhoondi A(2006). Sulphur containing compounds in the essential oil of Ferula persica Willd. var. persica. Flavour and Fragrance Journal, 21, 2, 260-261.
12- Shahverdi AR, Saadat F, Khorramizadeh MR, Iranshahi M, Khoshayand MR (2006). Two matrix metalloproteinase from Ferula persica var. persica. Phytomedicine, 13, 712-717.
13- Mosaffa F, Behravan J, Karimi G, Iranshahi M (2006). Antigenotoxic effects of Satureja hortensis L. on rat lymphocytes exposed to oxidative stress. Archives of Pharmacal Research, 29, 159-164.
14- Iranshahi M, Arfa P, Ramezani M, Jaafari MR, Sadeghian H, Bassarello C, Piacente S, Pizza C (2007). Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes. Phytochemistry, 68, 554-561.
15- Almasirad A, Amanzadeh Y, Taheri A,Iranshahi M (2007). Composition of a historical rose oil sample (Rosadamascena Mill. Rosaceae). Journal of Essential Oil Research, 19, 110-112.
16- Emami SA, Amin-Ar-Ramimeh E, Ahi A, Bolourian Kashy MR, Schneider B, Iranshahi M (2007). Prenylated flavonoids and flavonostilbenes from sophora pachycarpa roots. Pharmaceutical Biology, 45, 453-457.
17- Iranshahi M, Shaki F, Mashlab M, Porzel A, Wessjohann LA (2007). Kopetdaghins A-E, sesquiterpene derivatives from the aerial parts and the roots of Dorema kopetdaghense. Journal of Natural Products, 70, 1240-1243.
18- Shahverdi AR, Fakhimi A, Zarrini Gh., Dehghan Gh., Iranshahi M (2007). Galbanic acid from Ferula szowitsiana enhanced the antibacterial activity of penicillin G and cephalexin against Staphylococcus aureus. Biological and Pharmaceutical Bulletin, 30, 1805-1807.
19- Behravan J, Mosaffa F, Karimi GR, Iranshahi M (2007). In vitro protective effects of Satureja hortensis L. essential oil and ethanolic extract on lymphocytes DNA. Journal of Medicinal Plants, 6, 64-70.
20- Iranshahi, M, Emami SA, Mahmoud Soltani M (2007). Detection of sesquiteerpene lactones in ten Artemisia species population of Khorasan provinces. Iranian Journal of Basic Medical Sciences, 10, 183-188.
21- Shahverdi AR, Moradkhani R, Mirjani R, Alimirzaee P, Monsef Esfehani HR, Iranshahi M, Gohari Ar (2007). Enhancement effect of Berberis vulgaris var. integerrima seeds on the antibacterial activity of cephalosporins against Staphylococcus aureus and Escherichia coli. Iranian Journal of Pharmaceutical Sciences, 3, 181-186.
22- Barthomeuf C, Lim S, Iranshahi M, Chollet P (2008). Umbelliprenin from Ferula szowitsiana inhibits the growth of human M4Beu metastatic pigmented melanoma cells through cell-cycle arrest in G1 and induction of caspase-dependent apoptosis. Phytomedicine, 15, 103-111.
23- Iranshahi M, Mojarab M, Sadeghian H, Hanafi-Bojd MY, Schneider B (2008). Polar secondary metabolites of Ferula persica roots. Phytochemistry, 69, 473-478.
24- Iranshahi M, Kalategi F, Rezaee R, Shahverdi AR, Ito C, Furukawa H, Tokuda H, Itoigawa, M (2008). Cancer chemopreventive activity of terpenoid coumarins from Ferula species. Planta Medica, 74, 147-150.
25- Iranshahi M, Hassanzadeh-Khayat MH, Fazly Bazzaz BS, Sabeti Z, Enayati F (2008). High content of polysulphides in the volatile oil of Ferula latisecta Rech. F. et Aell. fruits and antimicrobial activity of the oil. Journal of Essential Oil Research, 20, 183-185.
26- Iranshahi M, Hassanzadeh-Khayyat MH, Sahebkar A, Famili A(2008). Chemical composition of the fruit oil of Ferula flabelliloba. Journal of Essential Oil Bearing Plants, 11, 143-147.
27- Karimi G, Hassanzadeh M, Yazdanpanah H, Nazari F, Iranshahi M, Nili A (2008). Contamination of patulin in clear apple juice in Mashhad, Iran. Journal of Food Safety, 28, 413-421.
28- Iranshahi M, Amanzadeh Y (2008). Rapid isocratic HPLC analysis of caffeic acid derivatives from Echinacea purpurea cultivated in Iran. Chemistry of Natural Compounds, 44, 190-193.
29- Iranshahi M, Fata A, Emami B, Jalalzadeh Shahri BM, Fazly Bazzaz BS (2008). In vitro antifungal activity of polysulfides-rich essential oil of Ferula latisecta fruits against human pathogenic dermatophytes. Natural Product Communications, 3, 1543-6.
30- Iranshahi M,Hassanzadeh-Khayyat M (2008). Chemical composition of the volatile oil from Ferula ovina (Boiss.) Boiss. – Rech. fruits. Journal of Essential Oil Bearing Plants, 11, 350-355.
31- Iranshahi M, Hosseini ST, Shahverdi AR, Molazadeh K, Suleman Khan S, Ahmad VU (2008). Diversolides A-G, guaianolides from the roots of Ferula diversivittata. Phytochemistry, 69, 2753-2757.
32- Noroozi S, Mosaffa F, Soltani F,Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J (2009). Antigenotoxic effects of the disulfide compound persicasulfide A (PSA) on rat lymphocytes exposed to oxidative stress. Planta Medica, 75, 32-36.
33- Behnam Rasouli F, Matin MM, Iranshahi M, Bahrami AR, Neshati V, Mollazadeh S, Neshati Z (2009). Mogoltacin enhances vincristine cytotoxicity in human transitional cell carcinoma (TCC) cell line. Phytomedicine, 16, 181-187.
34- Iranshahi M, Rezaee R, Sahebkar A, Bassarello C, Piacente S, Pizza C (2009). Sesquiterpene coumarins from the fruits of Ferula badrakema. Pharmaceutiacal Biology, 47, 344-347.
35- Asili J, Sahebkar A, Fazly Bazzaz BS, Sharifi S, Iranshahi M (2009). Identification of essential oil components of Ferula badrakema fruits by GC-MS and 13C-NMR methods and evaluation of its antimicrobial activity. Journal of Essential Oil Bearing Plants, 12, 7-15.
36- Iranshahi M, Chitsazian Yazdi M, Hassanzadeh-Khayyat M, Sahebkar A (2009). Sulfur containing compounds in the volatile oil of Ferula latisecta Rech. f. & Aell. leaves. Journal of Essential Oil Bearing Plants, 12, 64-68.
37- Soltani F, Mosaffa F, Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J (2009). Evaluation of antigenotoxicity effects of umbelliprenin on human peripheral lymphocytes exposed to oxidative stress. Cell Biology and Toxicology, 25, 291-296.
38- Moallem SA, Farahmand-Darzab A, Sahebkar A,Iranshahi M (2009). Antiemetic activity of different extracts from the aerial parts of Thymus vulgaris Klokov. Pharmacologyonline, 1, 1284-1292.
39- Askari M, Sahebkar A, Iranshahi M (2009). Synthesis and purification of 7-prenyloxycoumarins and herniarin as bioactive natural coumarins. Iranian Journal of Basic Medical Sciences, 12, 63-69.
40- Neshati V, Matin MM, Iranshahi M, Bahrani AR, Behravan J, Mollazadeh S, Behnam Rassouli F (2009). Cytotoxicity of vincristine on the 5637 cell line is enhanced by combination with conferone. Zeitschrift für Naturforschung, 64c, 317-322.
41- Iranshahi M, Sahbkar A, Takasaki M, Konoshima T, Tokuda H (2009). Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo. European Journal of Cancer Prevention, 18, 412-415.
42-Iranshahi M, Askari M, Sahebkar A, Hadjipavlou-Litina D (2009). Evaluation of antioxidant, anti-inflammatory and lypoxygenase inhibitory activities of the prenylated coumarin umbelliprenin. Daru, 17, 99-102.
43- Moghaddam KM, Iranshahi M, Chitsazian Yazdi M, Shahverdi AR (2009). The combination effect of curcumin with different antibiotics against Staphylococcus aureus. International Journal of Green Pharmacy, 3, 141-143.
44- Fazly Bazzaz BS, Rezaei Du A, Iranshahi M, Naderinasab M, Khajekaramodin M (2009). Evaluating the potentiating effect of galbanic acid from Ferula szowitsiana on three common antibiotics against resistant hospital isolates of Staphylococcus aureus. Iranian Journal of Pharmaceutical Research, 8, 217-221.
45- Iranshahi M, Noroozi S, Behravan J, Karimi G, Schneider B (2009). Persicasulphide A, a new sulphur-containinig derivative from Ferula persica. Natural product Research, 17, 1584-1588.
46- Soltani F, Mosaffa F, Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J (2010). Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress. Phythoterapy Research, 24, 85-89.
47- Iranshahi M, Sahebkar A, Hosseini ST, Takasaki M, Konoshima T, Tokuda H (2010). Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo. Phytomedicine, 17, 269-273.
48- Iranshahi M, Kalateghi F, Sahebkar A, Sardashti A, Schneider B (2010). New sesquiterpene coumarins from the roots Ferula flabelliloba. Pharmaceutical Biology, 48, 217-220.
49- Bagheri SM, Sahebkar A, Gohari AR, Saeidnia S, Malmir M, Iranshahi M (2010). Evaluation of cytotoxicity and anticonvulsant activity of some Iranian medicinal Ferula species. Pharmaceutical Biology, 48, 242-246.
50- Iranshahi M, Ghiadi M, Sahebkar A, Rahimi A, Bassarello C, Piacente S and Pizza C (2009). Badrakemonin, a New Eremophilane-Type Sesquiterpene from the Roots of Ferula badrakema Kos.-Pol. Iraninan Journal of Pharmaceutical Research, 8, 275-279.
51- Sahebkar A, Hassanzadeh-Khayyat M, Iranshahi M (2010). Quantitative analysis of the hydro-distilled essential oil of Ferula latisecta Rech. F. Aell. Roots from Iran.Journal of Essential Oil Bearing Plants, 13, 340-346.
52- Karimi G, Iranshahi M, Hosseinalizadeh F, Riahi B, Sahebkar A (2010). Screening of acetylcholinesterase inhibitory activity of terpenoid and coumarin derivatives from the genus Ferula. Pharmacologyonline, 1, 566-574.
53- Iranshahi M, Hosseini ST, Sahebkar A, Suleiman Khan S, Ahmad VU (2010). Diversivittatin, a new phenylpropanoid derivative from the roots of Ferula diversivittata. Chemistry of Natural Products, 46, 192-194.
54- Mollazadeh S, Matin MM,Iranshahi M, Bahrami AR, Neshati V, Behnam-Rasouli F (2010). The enhancement of vincristine cytotoxicity by combination with feselol. Journal of Asian Natural Products Research, 12, 569-575.
55- Fazly Bazzaz BS, Memariani Z, Khashiarmanesh Z, Iranshahi M, Naderinasab M (2010). Effect of galbanic acid, a sesquiterpene coumarin from Ferula szowitsiana, as an inhibitor of efflux mechanism in resistant clinical isolates of Staphylococcus aureus. Brazilian Journal of Microbiology, 41, 574-580.
56- Shahi M, Hanafi-Bojd AA, Iranshahi M, Vatandoost H, Hanafi-Bojd MY (2010). Larvicidal efficacy of latex and extract of Calotropis procera (Gentianales: Asclepiadaceae) against Culex quinquefasciatus andAnopheles stephensi (Diptera: Culicidae). Journal of Vector Borne Diseases, 47, 185-188.
57- Sahebkar A, Iranshahi M (2010). Cancer chemoprevention by 7-prenyloxycoumarins: a role for 5-lipoxygenase inhibition? Integrative Cancer Therapies, 9, 259-260.
58- Iranshahi M, Masullo M, Asili A, Hamedzadeh A, Jahanbin B, Festa M, Capasso A, Piacente S (2010). Sesquiterpene coumarins from Ferula gumosa. Journal of Natural Products, 73, 1958-1962.
59- Emami SA, Taghizadeh Rabe SZ, Iranshahi M, Ahi A, Mahmoudi M (2010). Sesquiterpene Lactone fr
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