News


The Pharmaceutical Research Center
Buali (Avicenna) Research Institute
Mashhad University of Medical Sciences
 
Pharmacodynamics Unit 
 
Pharmaceutical Research Center Pharmacodynamics Unit

Head:
           Dr. Hosseinzadeh, Hossein (PhD in Pharmacology)
Manager:
           Dr. Moatamedolshariati, Vahide sadat (Pharm.D.)

Activities:

  • Toxicological and pharmacological investigations of chemical agents and herbal medicines with emphasis on native plants such as Crocus sativus L. (Saffron) and Salvia leriifolia (Nourozak)

Investigations:

  • Antinociceptic effects of crocin and safranal in mice.

  • Protective effect of aqueous and ethanolic extracts of Salvia leriifolia on diminishing damages caused by renal ischemia in rats.

  • Protective effect of saffron aqueous extract and crocin, as one of the active constituent of saffron on diminishing damages caused by renal ischemia in rats.

  • Acute and subacute toxicity effects of crocin and safranal in rats

  • Antidepressant effect of N-substituted imidazole carboxamides in the forced swimming test model in mice.

  • Effects of aqueous extract of Pinus eldarica (pine fruit) in treatment or prevention of renal calcium oxalate formation.

  • Effects of Crocus sativus aqueous extract and its two constituents, crocin and safranal, in an experimental Multiple Sclerosis model in rats.

  • Protective effect of the saffron stigma in reduction of reperfusion syndrome lesions after vascular clamping of the lower limb

  • Effect of saffron aqueous extract and its two constituents, crocin and safranal, on the prevention of cataract caused by galactose in rats

 

 

Last Update : 2012-02-09 05:28:16

Pharmaceutical Research Center, BuAli Research Institute, BuAli Square, Mashhad -Iran, Postal Code: 9196773117, Tel.: (098 511) 7112470, Fax:( 098 511) 7112470, Email: PRC@mums.ac.ir
All rights reserved. No part of the contents of this Website may be reproduced or transmitted in any form or by any means, without the written permission