Personal Information:

First name: Hamid Reza

Last name: Sadeghnia

Date and place of birth: Apr 26. 1977, Kashmar, Iran

Marital status: Single

Nationality: Iranian

Mailing address: Department of Pharmacology, School of Medicine, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran.

Tel: +98-511-8828566, Fax: +98-511-8828567

E-mail: sadeghniahr@mums.ac.ir

  hsadeghnia@gmail.com 

Present position:

2008 until now: Assistant professor, Department of pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I.R. Iran

Educations:

2008: Ph.D. in Pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I.R. Iran

2002: Pharmacy Doctorate (Pharm.D.), Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I.R. Iran

Thesis: 

Evaluation of neuroprotective and genoprotective effects of safranal. Supported by the Research Council of Mashhad University of Medical Sciences, Mashhad, I.R. Iran.

Bioequivalence study of two formulations of ketoconazole tablet in healthy volunteers.

Appointments and professional activities:

Member of scientific committee of 18^th Iranian Congress of Physiology and Pharmacology, Mashhad, I.R. Iran (2007)

Coordinator of workshop affairs in 18^th Iranian Congress of Physiology and Pharmacology, Mashhad, I.R. Iran (2007)

IT coordinator, Department of pharmacology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I.R. Iran (2008)

Member of scientific committee of 2^nd International and 9^th Annual Congress of Iranian Medical Students (2008)

Member of scientific committee of 1^st International Congress of Veterinary Pharmacology and Pharmaceutical Sciences (2008)

Research Experience: 

Electrophoresis and chromatographic methods

Streotaxic surgery

Brain microdialysis and analysis of neurotransmitters

Autoradiography and binding assay

ECoG and extracellular recording

Comet assay (single cell gel electrophoresis)

Publications:

Articles:

Sadeghnia HR, Nassiri-Asl M, Haddadkhodaparast MH, Hosseinzadeh H. The effect of Salvia Leriifolia Benth. root extract on lipid peroxidation level during global ischemic-reperfusion injury in rat hippocampus. J Med Plants, 2003, 2: 19-28.

Boroushaki MT, Sadeghnia HR, Mofidpour H. Protective effect of calcium channel blockers against hexachorobutadiene nephrotoxicity in rat. Iran J Basic Med Sci, 2005, 7: 208-214.

Sadeghnia HR, Hassanzadeh-khayyat M. Bioequivalence study of two formulations of ketoconazole tablet in healthy volunteers. Iran J Pharmaceut Sci, 2005, 1(4): 209-215.

Sadeghnia HR, Boroushaki MT, Mofidpour H. Effect of safranal on lipid peroxidation level during renal ischemia-reperfusion injury in rat. Iran J Basic Med Sci, 2005, 8: 179-185.

Hosseinzadeh H, Sadeghnia HR, Ziaee T, Danaee A. Protective effect of aqueous saffron extract (Crocus sativus L.) and crocin, its active constituent, on renal ischemia-reperfusion-induced oxidative damage in rats. J Pharm Pharmaceut Sci, 2005, 8(3):387-393.

Hosseinzadeh H, Sadeghnia HR. Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus.J Pharm Pharmaceut Sci, 2005, 8(3): 394-399.

Boroushaki MT, Mofidpour H, Sadeghnia HR. Protective effect of safranal against hexachorobutadiene-induced nephrotoxicity in rat. Iran J Med Sci, 2007, 32 (3): 173-176.

Hosseinzadeh H, Hosseini A, Nassiri-Asl M, Sadeghnia HR. Effect of Salvia leriifolia Benth. root extracts on ischemia-reperfusion in rat skeletal muscle. BMC Complement Altern Med, 2007, 7: 23-45.

Hosseinzadeh H, Sadeghnia HR. Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: Involvement of GABAergic and opioids systems. Phytomedicine, 2007, 14: 256-262.

Hosseinzadeh H, Sadeghnia HR. Effect of safranal, a constituent of Crocus sativus (saffron), on methyl methanesulfonate (MMS)-induced DNA damage in mouse organs: An alkaline single cell gel electrophoresis (comet) assay. DNA Cell Biol, 2007, 26 (12), 841-846.

Hosseinzadeh H, Parvardeh S, Asl MN, Sadeghnia HR, Ziaee T. Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus. Phytomedicine, 2007, 14(9):621-627.

Sadeghnia HR, Cortez M, Liu D, Hosseinzadeh H, Snead 3^rd, OC. Antiabsence effects of safranal in acute experimental seizure models: EEG and autoradiography.J Pharm Pharmaceut Sci 2008; 11(3): 1-14. 

Hosseinzadeh H, Sadeghnia HR, Rahimi A. Effect of safranal on extracellular hippocampal levels of glutamate and aspartate during kainic acid seizures in anesthetized rats. Planta Med 2008; 74(12): 1441-5.

Hosseinzadeh H, Abootorabi A, Sadeghnia HR. Protective effect of Crocus sativus stigmas extract and crocin (trans-crocin 4) on methyl methanesulfonate (MMS)-induced DNA damage in mice organs. DNA Cell Biol 2008 Sep 13 [Epub ahead of print].

Sadeghnia HR, Cortez M, Liu D, Snead 3^rd, OC. Effect of adrenocorticotropic hormone (ACTH) on γ-butyrolactone (GBL)-induced absence seizures in wild type and Ts65Dn mice. Iran J Med Sci (In press).

Abstracts and Congress presentations:

Sadeghnia HR, Nassiri Asl M, Haddadkhodaparast MH, Hosseinzadeh H (2005). The effect of Salvia Leriifolia Benth. Root extract on lipid peroxidation level during global ischemic-reperfusion injury in rat hippocampus. National Congress in Sustainable Development of Medicinal Plants, Mashhad, Iran, July 27-29.

Sadeghnia HR, Hosseinzadeh H (2005). Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus. 17^th Iranian Congress of Physiology and Pharmacology, Kerman, I.R. Iran, September 30-October 3.

Hosseinzadeh H, Sadeghnia HR (2005). Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus. International Conference on Medicinal Plants, Kuala Lumpur, Malaysia, December 5-7.

Sadeghnia HR, Hosseinzadeh H. Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: Involvement of GABAergic and opioids systems. 18^th Iranian Congress of Physiology and Pharmacology, 26-30 August 2007, Mashhad, I.R. Iran.

Hosseinzadeh H, Sadeghnia HR (2007). Effect of safranal fromCrocus sativus on extracellular hippocampal levels of glutamate and aspartate during kainic acid seizures in anesthetized rats. 55^th International Congress and Annual Meeting of the Society for Medicinal Plant Research. Gratz, Austria, September 2-6. Planta Med. 73: 968.

Lecture:

Sadeghnia HR. Antiabsence effects of safranal in acute experimental seizure models: EEG and autoradiography, Medical Science Building, University of Toronto, 19 November 2006, Toronto, Canada.

Workshops:

Training Course on Electrophysiological Workshop of Satellites FAONS Symposium, April 2005, Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, I.R. Iran.

Training Course on Cell Culture Workshop of 18^th Iranian Congress of Physiology and Pharmacology, August 2007, Mashhad University of Medical Sciences, School of Medicine, Mashhad, I.R. Iran.

Training Course on Evaluation of Drug Effects on Nociception, Ischemia, Seizure, Hypertension, Learning and Memory Workshop of 18^th Iranian Congress of Physiology and Pharmacology, August 2007, Mashhad University of Medical Sciences, School of Medicine, Mashhad, I.R. Iran.

Training Course on Advance Technologies in Neuroscine Workshop, February 2008, Mashhad University of Medical Sciences, School of Medicine, Mashhad, I.R. Iran.

References:

Dr. Hossein Hosseinzadeh, Professor of Pharmacology, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

E-mail: hosseinzadehh@mums.ac.ir

سDr. Mohammad Taher Boroushaki, Assistant professor of Pharmacology, Faculty of Medicince, Mashhad University of Medical Sciences,Mashhad, Iran.

E-mail: m-boroushaki@mums.ac.ir

تاريخ بروز رساني : چهارشنبه 07/07/89 ساعت 11:07