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Results from eleven independent ALS (Lou Gehrig's Disease) research studies are giving hope to the ALS community - showing for the first time that the disease may be treatable by targeting new mechanisms revealed by neural stem cell-based studies. A decade of research conducted at multiple institutions, shows that when neural stem cells were transplanted into multi-levels of the spinal cord of a mouse model with familial ALS, disease onset and progression slowed, motor and breathing function improved and treated mice survived three to four times longer than untreated mice. A summary of the findings from all eleven studies published online December 19 in Science Translational Medicine.

"This significant research will help us better understand the mechanisms underlying motor neuron diseases," said Yang (Ted) Teng, PhD, MD, the study's co-lead author and director of the Spinal Cord Injury and Stem Cell Biology Research Laboratory in the Department of Neurosurgery at Brigham and Women's Hospital. "This work sheds new light on detrimental roles played by non-neuronal cells in triggering motor neuron death and these events should be targeted for developing more effective therapeutics to treat ALS."
 
 
 
 

 

Stem Cell Research Shows ALS May Be Treatable

Last Update : 2017-12-13 04:38:20

Mashhad University of Medical Sciences Contact Details:
Main address: University St., Ghoraishy Building 91375-345 Mashhad, Iran ,
Tel:( 98 511) 841 2081-5 , Fax:( 98 511) 8430249 , E-mail: Info(at)mums.ac.ir Members: - Schools and Hospitals School: Dentistry , School: Health , School: Medicine , School: Nursing & Midwifery , School: Paramedical , School: Pharmacy , School: Traditional Medicine , Hospital: Dr.Sheikh , Hospital: Dr.Shariati , Hospital: Emam Reza , Hospital: Ghaem , Hospital: Hashemi Nezhad , Hospital: Ibn-e-Sina , Hospital: Khatam-al-Anbia , Hospital: Montaserie , Hospital: Ommul-Banin , Hospital: Omid , Hospital: Shahid Kamyab , Hospital: Taleghani , History: Mashhad Faculty of Medicine was officially opened on Nov. 23, 1949 by Dr Zanganeh, the minister of culture. The school started out with 61 students, one associate professor and seven tutors. In 1956, when the school of Arts opened, the two schools merged to form the University of Mashhad. In 1989, the faculties offering Medical Sciences' degrees across the country separated from the Ministry of Culture and Higher Education. New emerging Medical Universities have gone under management of Ministry of Health, Treatment and Medical Education. Thus the original University of Mashhad was divided into two independent universities: "Ferdowsi University of Mashhad" and "Mashhad University of Medical Sciences'. Mashhad University of Medical Sciences operates at present with 8 faculties, 32 hospitals, 179 rural and 147 urban health centers. It covers an enormous area stretching from the north east to the central parts of the country, which makes it the largest university of Medical Sciences providing health care and treatment services. With 597 teaching staff, 1645 MDs with different specialties, 138 dentists, 123 pharmacists and 25, 402 employees, the university provides health care and medical services to the area's large population as well as to over 25 million tourists a year.

Mashhad university of medical Sciences, Information Technology Center, Imam Reza Hospital, Mashhad-Iran, Tel.:(+98 51) 38023024-6, Fax:(+98 51) 38548048, P.O. Box: 91375-3316, SMS: 30007273, Email: web@mums.ac.ir
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