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MUMS Immunology Research Center
Human Genetics Unit
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Head:
Staff:
Dr. Mehran Gholamin, PhD in Immunology
Dr. omranpoor, Oncologist
Dr. Arash Velayati, MD
Dr. Omid Moaven, MD
Mrs. Marta Ghahreman, MSc in genetics
Mrs Mitra Alizade Nakhaee, MSc in biochemistry
Dr. Noshin Taghavi, PhD in genetics
Mr. Ezat Dadkhah, MSc
Mrs. Azadeh Aarabi, BSc in microbiology
Mr. Moeen Farshchian, MSc in microbiology
Mrs Somaye Chavochi, MSc
Mrs Masome Maleki, MSc
Mrs Tina Abrishami, MSc in biochemistry
Mrs Adele Razavipoor, MSc in biochemistry
Mr. Saeedreza Sardari, MSc in biochemistry |
Human genetics research activities:
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Evaluation of Novel Molecular tumor markers for early diagnostic and prognostic purpostic in GI. Cancers
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Establishment of cell line for esophageal squamous cell carcinoma (ESCC)
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ESCC mRNA transfer in dendritic cells and immuno-genetherapy of ESCC cancer
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Molecular characterization of mutant genes in Gentic diseases (i.e. Congenital Adrenal Hyperplasia)
Dicovery & Patent:
Gene Bank new sequence submissions
Gene Bank Accession No. gene Mutation
EU236681 CYP21A2 gene (G.2336T>C)
EU236682 CYP21A2 gene (G. 2569A>C)
EU236683 CYP11b1 gene (InsAG393)
EU681276 APC D4587V
EU681189 APC codon4581ATG(M)
EU681190 B-Catenin del A in codon 76
EU681277 B- Catenin S to T at codon 47
GU201906.1
GU170814
Instruments:
- Thermocyclers
- Refrigerator and freezer
- Real time PCR
- Heater
- Ultracentrifuge
- Rotator
- Vacuum system
- Oven
- Incubators
- Microcentrifuge
- Hood
- UV lamp
- Centrifuge
- Shaker
- Mini Spin
- Homogenizer
- UV Transilluminator
- electrophoresis
- Digital balance
- Power supply
Published Articles:
 Interactions between Glutathione-S- Transferase M1, T1 and P1 polymorphisms and smoking, and increased susceptibility to esophageal squamous cell carcinoma. Moaven O, Raziee HR, Sima HR, Ganji A, Malekzadeh R, Arabi A, Abdollahi A, Memar B, Setoudeh M, Naseh H, Nekoui N, Razavipour A, Gholamin M, Dadkhah E, Farshchian M, Abbaszadegan MR:Cancer Epidemiology, 34(3): 285-90, 2010
Induction of cytotoxic T lymphocytes primed with Tumor RNA-loaded Dendritic Cells in Esophageal Squamous Cell Carcinoma: preliminary step for DC vaccine design. Gholamin M, Moaven O, Farshchian M, Mahmoudi M, Sankian M, Memar B, Rajabi-Mashhadi MT, Forghani MN, Malekzadeh R, Abbaszadegan MR: BMC Cancer, 2010.
Highly Efficient Transfection ofDendritic Cells with GFP mRNA: Optimization Tool for Immuno-genetherapy of Esophageal Squamous Cell Carcinoma. Gholamin M, Moaven O, Farshchian M, Rajabi-Mashhadi MT, Mahmoudi M, Sankian M, Sazgarnia A, Ghahreman M, Abbaszadegan MR: Ir J Biotech 8(2), 121-126, 2010
p16INK4ahypermethylation and p53, p16 and MDM2 protein expression in Esophageal Squamous Cell Carcinoma. Taghavi N, Biramijamal F, Sotoudeh M, Khademi H, MalekzadehR, Moaven O, Memar B, A’rabi A, Abbaszadegan MR: BMC Cancer, 13;10:138, 2010
P21 (Waf1/Cip1) gene polymorphisms and possible interaction with cigarette smoking in esophageal squamous cell carcinoma in northeastern Iran. Taghavi N, Biramijamal F, Abbaszadegan, MR, Khademi H, Sotoudeh M, Khoshbakht S, Malekzadeh R: Arch Ir Med, 13(3):235-42, 2010
Five cases of severe vesico-ureteric reflux in a family with an X-linked compatible trait. Naseri M, Ghiggeri GM, Caridi G, Abbaszadegan MR: Pediatr Nephrol. 25(2):349, 2010.
Microsatellite Instability in Young Iranian Women with Endometrioid type Endometrial Cancer. Abbaszadegan MR, Asadzadeh Aghdayi H, Rastin F, Dadkhah E, Lotfalizadeh M, Mohamadian Roshan N, Farzadnia M, Velayati A, A'rabi A:Ir J Public Health, 38(3): 24-30, 2009
Clinicopathological significance of E-cadherin, β-catenin and p53 expression in gastric adenocarinoma. Zali MR, Moaven O, Asadzadeh-Aghdaee H, Ghafarzadegan K, Jami Al-Ahmadi K, Farzadnia M, Arabi A, Abbaszadegan MR: J Res Med Sciences, 14:239-247, 2009
Overexpression and Interactions of IL-10, TGF-β and VEGF mRNA Expression in ESCC. Ghoamin M, Moaven O, Farshchian M, Memar B, Naseh H, Malekzadeh R, Sotoudeh M, Rajabi-Mashhadi MT, Forghani MN, Farrokhi F, Abbaszadegan MR: World J Surgery, 33(7):1439-45, 2009
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human genetics mashhad university of medical science MUMS Immunology Research Center
h medical science |
Last Update : 2012-02-09 05:14:12
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Immunology