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 مرکز تحقیقات چشم>شورای پژوهشی>اولویت ها>سازمان جهانی بهداشت
 
 

A Research Agenda for Global Blindness Prevention

The global initiative known as VISION 2020: the Right to Sight .The goal is eliminating avoidable blindness by the year 2020.

Blindness’ is defined as visual acuity of less than 3/60, or a corresponding visual field loss to less than 10, in the better eye with the best possible correction.‘Low vision’ is defined as visual acuity of less than 6/18 but equal to or better than 3/60, or a corresponding visual field loss to less than 20, in the better eye with the best possible correction. ‘Visual impairment’ includes both low vision and blindness

Global causes of blindness due to eye diseases and uncorrected refractive errors

Vision research to support Vision 20/20 and Vision for the Future

  1. Cataract
Prevention: 
cataractogenesis requires innovative epidemiologic studies seeking factors that
increase the risk of disease (short- to medium-term) and mechanistic studies of
lens biology (medium- to long-term).
Cataract Surgery:
Compare the cost-benefit of cataract surgery performed at different levels ofvisual acuity (adjusted for visual demands).Assess factors that determine local indications for cataract surgery, and theirappropriateness
Identify resources and incentives required to motivate/train existing cataract
surgical manpower to better meet quality standards and higher surgical volumes
Evaluate cataract surgical rate (cataract operations per million population per year).
2. Trachoma
Trichiasis Surgery(Research issues)
Improving surgical outcome of trichiasis surgery. At present, the relapse
rate, even for well-trained ophthalmic surgeons, is high. Identify factors that influence the recurrence of trichiasis following seemingly successful lid surgery? Develop improved surgical approaches (by employing the latest plastic surgery techniques), and test these in clinical trials.
Identify barriers to surgical uptake and ways to reduce cost and
increase access (e.g., minimal equipment and supplies; efficient and
effectives procedures and the training of lid surgeons; ways to increase
demand/compliance).
4. Xerophthalmia
control micronutrient malnutrition
UNICEF estimates these reach 80% of their target childhood populations in over 40 countries.
Develop better tools for population assessment of vitamin A status and the impact of Vit A deficiency on ocular structures and ocular immune system.
5. The Glaucomas
Research Opportunities (for various yype of glaucoma)
population-based intervention: screening techniques are needed that identify subgroups at particularly high risk of disease (genetic markers?) Epidemiologic studies may identify environmental/behavioral factors that contribute to (seemingly) societal variations in risk
Simplified and sensitive measures of progression of optic nerve damage would dramatically improve the ability to test alternative interventions and improve the benefits of intervention/management
New and novel treatment approaches, particularly neuroprotection (beyond medical and surgical approaches targeting IOP), would offer new options for control of blinding disease
6. Diabetic Retinopathy
Diabetic retinopathy is a rapidly growing problem. global epidemic of obesity is fueling a dramatic increase in the incidence of NIDDM.
Operations research may targeted to those at high risk because of genetic or nutritional factors.
Documenting population variations in risk of DRP may help elucidate genetic and environmental markers/pathogenetic mechanisms
The nature of angiogenesis and its relation to antioxidant intake may better be studied in micronutrient poor populations
Better tools are needed for defining risk, early disease, and tracking progression
7.Age-Related Macular Degeneration
The number affected is expected to double by the year 2020 as a result of the ageing of the world’s population
Aim: to prevent and reduce vision loss from age-related macular degeneration and improve functioning vision and quality of life of persons with functional low vision
Operations Research:
Effectiveness of different treatment methods
Epidemiologic Risk Profile:
Documenting population variations in risk
Environmental markers/pathogenetic mechanisms
Basic Biologic Research :
Genetic markers/pathogenetic mechanisms
Transplantation of retinal pigment epithelial and neural retinal cells
Drug delivery systems
8. Refractive Error
Refractive error is the most common ocular abnormality The two major refractive disorders impacting on employment and quality of life are myopia and presbyopia (aside from surgical aphakia).
Research Opportunities
Enroll high risk populations into epidemiologic studies and randomized clinical trials seeking environmental/behavioral etiologic factors and effective strategies for reducing the incidence/progression of refractive error
Investigate the value of social marketing of refraction/spectacles
Identify the origins of myopia
Investigate alternative interventions for reducing the incidence/progression of refractive error
Low vision is currently defined as ‘visual acuity of < 6/18 down to and including 3/60 in
The better eye’, from all causes. Enhance vision-related quality of life for people with functional low vision
9. Childhood blindness 
Childrens’ eyes cannot, however, be considered smaller versions of adults’ eyes, and specific expertise and equipment are required
Unlike adults, children require longterm follow-up after surgery, to manage complications and to prevent amblyopia
The causes of the main avoidable childhood blindness are:
Corneal scarring
Cong cataract
Cong glaucoma
Retinopathy of prematurity
Refractive errors and low vision, which encompasses visual impairment and blindness from untreatable causes
10.Human resource development
Human resource development is the second component of the strategy for eliminating avoidable blindnessby 2020
The goal is to have in place a sustainable, equitable, comprehensive eye-care system
as an integral part of national health systems
Aim: to have in place an appropriately trained, functional, multidisciplinary workforce, that will focus on the coverage, quality and sustainability of eye health services
Train ophthalmologists in the required sub-specialities
11.Technology
Ensure an optimal supply of appropriate, high-quality, affordable equipment, instruments, consumables and resource materials essential for the delivery of eye-care services
Monitor new products to determine their suitability
 
 

 

 

تاريخ بروز رساني : سه شنبه 10/09/88 ساعت 08:14

Mashhad University of Medical Sciences Contact Details:
Main address: University St., Ghoraishy Building 91375-345 Mashhad, Iran ,
Tel:( 98 511) 841 2081-5 , Fax:( 98 511) 8430249 , E-mail: Info(at)mums.ac.ir Members: - Schools and Hospitals School: Dentistry , School: Health , School: Medicine , School: Nursing & Midwifery , School: Paramedical , School: Pharmacy , School: Traditional Medicine , Hospital: Dr.Sheikh , Hospital: Dr.Shariati , Hospital: Emam Reza , Hospital: Ghaem , Hospital: Hashemi Nezhad , Hospital: Ibn-e-Sina , Hospital: Khatam-al-Anbia , Hospital: Montaserie , Hospital: Ommul-Banin , Hospital: Omid , Hospital: Shahid Kamyab , Hospital: Taleghani , History: Mashhad Faculty of Medicine was officially opened on Nov. 23, 1949 by Dr Zanganeh, the minister of culture. The school started out with 61 students, one associate professor and seven tutors. In 1956, when the school of Arts opened, the two schools merged to form the University of Mashhad. In 1989, the faculties offering Medical Sciences' degrees across the country separated from the Ministry of Culture and Higher Education. New emerging Medical Universities have gone under management of Ministry of Health, Treatment and Medical Education. Thus the original University of Mashhad was divided into two independent universities: "Ferdowsi University of Mashhad" and "Mashhad University of Medical Sciences'. Mashhad University of Medical Sciences operates at present with 8 faculties, 32 hospitals, 179 rural and 147 urban health centers. It covers an enormous area stretching from the north east to the central parts of the country, which makes it the largest university of Medical Sciences providing health care and treatment services. With 597 teaching staff, 1645 MDs with different specialties, 138 dentists, 123 pharmacists and 25, 402 employees, the university provides health care and medical services to the area's large population as well as to over 25 million tourists a year.

مشهد، بلوار قرنی، چهارراه ابوطالب، بیمارستان خاتم الانبیاء(ص)، مرکز تحقیقات چشم تلفن :37281401 051 نمابر: 37289911 051 پست الکترونيک: erc@mums.ac.ir
تمام حقوق مادی و معنوی این سایت مربوط به دانشگاه علوم پزشکی مشهد می باشد و هرگونه کپی برداری از مطالب آن تنها با ذکر منبع بلامانع است.