A case of subglotitic adenoid cystic carcinoma and medical literature review
Naghibzadeh M. MD, *Hosseini S. MD, Sedaghat Sharifi N. MD
Abstract
ntrocuction: Adenoid cystic carcinoma (ACC) is the second most common salivary glands tumor and the most common malignant tumor of minor salivary glands and also submandibular glands; however ACC of the larynx and trachea is rare. These tumors generally present in subglottic region as smooth submucosal solid mass without ulceration. Their primary symptoms are often as respiratory problems.
Materials and Methods: This study was done on a woman, 54 years, with subglottic ACC that presented with exertional dyspnea, stridor, cough and hoarseness. After confirmation of diagnosis with biopsy, the patient underwent a total laryngectomy and then postoperative radiotherapy.
Conclusion: During one year follow up, the patient did not show any evidence of local recurrence or distant metastasis. Surgery with free margins in combination with postoperative radiotherapy was recommended to treat laryngeal ACC in order to obtain better survival.
Keywords: Adenoid cystic carcinoma, Larynx, Trachea
*Address: Department of otorhinolaryngology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
Email: hosseinis@mums.ac.ir
Received date: Dec 06, 2009 Accepted date: Apr 10, 2010
مجله گوش گلو و حنجره ايران
